Having never previously seen any Oprah Winfrey interviews, I've no idea whether her interviewees have to agree beforehand to answer any "Yes/No" questions she might ask with a straight "Yes" or "No".
But that's what disgraced cyclist Lance Armstrong did in this sequence from his interview with her.
Whether or not it was not the way she had expected him to confess, as she'd said in her trailers for the show, I do not know. I do know, however, that to my English ears, such apparently straight answers to a series of "Yes/No" questions definitely qualifies it for a place my collection of unusual TV interviews.
Examples of Other Unusual Interviews